Weight loss consistently ranks as the number-one New Year's resolution. But what if you've already lost a significant amount of weight? Like, 100-plus-pounds significant?

That's a good question for any of the women who lost 300, 500, or even more pounds on TLC's My 600-Pound Life, which chronicles the emotional journeys of men and women desperate to save their lives through drastic weight loss. Guests on the show have to learn how to revamp not only their entire lifestyles, but rethink everything they ever knew about themselves—from how they handle upsetting situations to dealing with past trauma to getting help for addictions. Yet despite all the difficulties, they do it, and do it well. 

Related: This Is One Of The Biggest Weight-Loss Lessons You Can Learn From 'My 600-Pound Life'

Check out this exclusive video clip from the sixth season of TLC's 'My 600-Pound Life,' which debuts Wednesday, January 10 (at 8 p.m. Eastern time—set your DVR!):

preview for My 600-Lb Life Season 6 Preview

For people who've lost hundreds of pounds, it’s important to realize that the real work starts after weight loss. “Our goal at that point is something many weight-loss programs don’t discuss much: maintenance," says Tony Stephan, R.D., C.P.T., a registered dietitian and ACE-certified personal trainer, who has helped clients lose 100-plus pounds. "You can be good at losing the weight, but keeping it off over the long term is the important part."

So, for someone who has lost weight, and wants to maintain or even lose more, a good New Year’s resolution should be about building on the healthy habits you’ve already formed, making sustainable lifestyle changes, and thinking about what you want your health to look like way more than a year from now, he says.

Here, women who lost weight on My 600-Pound Life share how they will continue their journeys in 2018. We bet their New Year's resolutions will inspire you to make a few positive changes of your own!

Nikki

Starting weight: 649 pounds
Current weight: 240 pounds

"My goal for this year is to continue on this road to wellness," says Nikki, of Little Rock, Arkansas. She recently got married and she sees 2018, plus her 409-pound weight loss, as an opportunity to start a whole new, healthier, life with her husband. "My main goal is to make sure that good health is a priority in our home," she explains.

What does this look like for her? In the year ahead, she resolves to start planning meals ahead of time, pre-packing healthy grab-and-go lunches they can take to work, and scheduling time in their calendars for regular workouts. The last piece of the puzzle is taking care of her mental health just as much as her physical health, including talking to a therapist, she adds.

Related: These ‘My 600-lb. Life’ Success Stories Will Blow Your Mind

Melissa

Starting weight: 653 pounds
Current weight: 255 pounds

"My hope for 2018 is not just to exercise more, but to be more active [outside of structured exercise]," says busy Texas mama Melissa, who has already lost 398 pounds. That means walking to the park with her kids, playing a quick game of tag with them before dinner, or simply choosing to stand rather than sit. It doesn't matter whether she's in the gym or not—she's going to stay moving.

Great idea. After all, Northwestern University research shows that even women who meet exercise recommendations sit just as much as their non-exercising counterparts do.

This is the easiest way to get more active:

preview for The Easiest Way To Get More Active

Brittani

Starting weight: 605 pounds
Current weight: 185 pounds

"In 2018, I want to maintain my healthy weight, but I also want to continue with my counseling," says Brittani, who has lost 420 pounds. "Going to therapy is a very important aspect of my weight loss."

As she's gone through the grueling process of overhauling her nutrition and getting consistent with exercise, the Houston, Texas, woman says she's learned that health is about so much more than the number on the scale. In fact, it's about so much more than just her body. "I believe happiness comes from balancing mind, body, and soul," she explains.

June

Starting weight: 585 pounds
Current weight: 277 pounds

"My main goal is to hit my goal weight of 205 pounds," says June, of Houston, Texas. She's already off to a great start. After losing 308 pounds, she's within 72 pounds of her goal weight. But she's not just focusing on the scale For her, it's all about having goals in different areas of her life, including improving her fitness and even her business skills. "My other goals for 2018 are to walk a 5K race and own another company," she adds. Bam!

Hey, when you're vying for long-term success, it's important to consider everything that empowers you to reach your potential, Stephan says.

(The Slim, Sexy, Strong Workout DVD is the fast, flexible workout you've been waiting for!)

Diana

Starting weight: 601 pounds
Current weight: 223 pounds

Diana, from Houston, Texas, is down 378 pounds, but she's still working on losing a few more. Her strategy: deal with her emotional eating, head-on. "In 2018, I am going to continue to work on addressing my weight issues with diet and exercise," she says. "But I'm also going to work on identifying my triggers that drive me to overeat and finding healthier options to deal with them."

Diana certainly isn't the only person to struggle with using food as a coping mechanism, and the best way to deal with that is to create small, sustainable changes that turn into healthy habits over time, Stephan says. Soon enough, those will become automatic, replacing old responses.

Related: 'I Lost 150 Pounds Thanks To This Exercise Routine'

Christina

Christina
My 600 Lb Life/TLC

Starting weight: 708 pounds
Current weight: 175 pounds

Losing weight is only one part of the process of getting healthy and Christina, of Houston, Texas, wants to make sure she's covering all the bases. Losing an impressive 533 pounds was a great start, but she says that she's ready for a new challenge in 2018. "My goal for next year is to focus on strength training," she says. Getting strong is a great goal, Stephan says, as lifting weights not only builds muscle and speeds up your metabolism, but it also increases confidence in your body and its abilities.

In fact, women who lift weights significantly improve their body images, according to a study published in the Journal of Extension. This boost is exactly what Christina craves; she says she's done with self-hate and low self-esteem. "I want to focus on learning to love the skin I’m in," she adds. And she should, she's worked hard for that skin (and everything inside it).